Dr. Silverman shares Life2000’s positive impact on his patients’ quality of life

Hear about Dr. Brown’s experience with wearABLE Open Ventilation

Reduces dyspnea and increases exercise endurance for patients with COPD

Breathe Technologies’ wearable and open ventilation* decreases work of breathing (WOB), respiratory muscle activation, and dyspnea, allowing for improved exercise tolerance and 6-minute walk tests (6MWT) compared to traditional oxygen therapy.1-6

  • reduction in healthcare costs and healthcare utilization such as inpatient admissions and mechanical ventilation days7
  • reduction in patient-reported CAT and mMRC scores2
  • reduction in WOB1
  • 46% reduction in accessory respiratory muscle activation3
  • 28% reduction in Borg Dyspnea Scale3
  • 54% increase in exercise endurance from 11.4 to 17.5 minutes (P < .001)3
  • 34 to 73 m improvement in 6MWT distance4,5
  • 85% improvement in ability to perform activities of daily living6

To view clinical studies, visit our Document Center

Impact of improving mobility and activity levels

  • Activity for 2 hours a week reduces hospital admissions and respiratory mortality by 30% to 40%, according to a 20-year follow-up study of 2,386 subjects with COPD8
  • Outdoor activity increases 4-year survival 35% versus 15% for oxygen-dependent patients9
  • Physical activity is the best predictor of all-cause mortality in COPD patients; for every 0.14 decrease in physical activity level (PAL), the relative risk of death is more than doubled10

*The data presented are reflective of studies performed on open ventilation technology.


1. Siobal M, Marelowe J. Work of breathing using non-invasive open ventilation in a low compliance high minute ventilation lung model. [abstract]. AARC 2015. 2. Carlin BW, Casey L, Farberow K. Improvement in health status of patients with respiratory insufficiency with the use of a noninvasive open ventilation system. Chest. 2014;146(4 MeetingAbstracts):341A. 3. Porszasz J, Cao R, Morishige R, et al. Physiologic effects of an ambulatory ventilation system in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013;188(3):334–342. 4. Hilling L, Cayou C, Wondka T, Kops R. Improved 6MWT distance with a highly portable non-invasive ventilator [abstract]. Am J Respir Crit Care Med. 2010;181:A1198. 5. Garvey C, Hilling L, Cayou C, Escobar R, Heron G, McCabe L. Open, noninvasive ventilation using a 1 lb ventilator, oxygen, and a low profile mask improves 6MWT distances in advanced COPD [abstract]. Am J Respir Crit Care Med. 2011;183:A3971. 6. Carlin BW, Wiles KS, McCoy RW, et al. Effects of a highly portable noninvasive open ventilation system on activities of daily living in patients with COPD. J COPD F. 2015;2(1):35-47. 7. Morishige R, Farberow K, MacIntyre N. Health care utilization and respiratory health status in patients with chronic respiratory insufficiency following addition of a portable noninvasive ventilator to the treatment regimen. Chest. 2015;148(4 MeetingAbstracts):908A. 8. Garcia-Aymerich J, Lange P, Benet M, et al. Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population-based cohort study. Thorax. 2006;61:772-778. 9. Ringbaek TJ, Lange P. Outdoor activity and performance status as predictors of survival in hypoxaemic chronic obstructive pulmonary disease (COPD). Clin Rehabil. 2005;19(3):331-338. 10. Waschki B, Kirsten A, Holz O, et al. Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest. 2011;140(2):331-342.

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